National Journal of Advanced Research

National Journal of Advanced Research


National Journal of Advanced Research
National Journal of Advanced Research
Vol. 7, Issue 2 (2021)

Relation of prolactin hormone with fibroadenosis and fibrocystic disease in breast


Rafah Younis Abdulrhman, Eman Mohammad Ali, Asil Ghanim Hamdoon

Background: Fibrocystic and fibroadenosis are the most common conditions that can be seen. Almost 40% of 20 to 50 years old women due to sensitivity to estrogen and progesterone hormone. Prolactin hormone play an important role in the proliferation and differentiation of normal breast epithelium and milk production from breast. Objectives: The study mainly aimed to evaluate the association between the level of the prolactin hormone and fibrocystic, fibroadenosis diagnosed by ultra sound in comparison with other group of same symptoms having normal ultra sound. Materials and Methods: Total 100 patients at 20 to 50 years old women. 83 of them having fibroadenosis and 17 of them having fibrocystic breast changes, baseline by ultra sound. Also 100 Patients at same age were complained of same symptoms with normal ultra sound reports. Two groups send for estimation of serum prolactin hormone level. Results: The results show that no strong relation between prolactin hormone and fibrocystic or fibroadenosis of breast. Abnormal prolactin level in 37.3% of fibroadenosis and 29.4% of fibrocystic changes,while normal level 62.7% and 70.6% respectively,in comparison with control group show 98% was normal level which was significant high. Also show high prevalence of fibroadenosis at age of 17-36 years old and fibrocystic at age 37-45 years old. There was relation between the changes with positive family history of breast cancer. The changes can affect one breast or both at same time. Conclusion: The study concludes that there was no strong relation between prolactin hormonal level and fibrocystic and fibroadenosis changes of breast and there was relation of changes with positive family history of breast cancer.
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How to cite this article:
Rafah Younis Abdulrhman, Eman Mohammad Ali, Asil Ghanim Hamdoon. Relation of prolactin hormone with fibroadenosis and fibrocystic disease in breast. National Journal of Advanced Research, Volume 7, Issue 2, 2021, Pages 05-07
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